Virulence factor p60 ofListeria monocytogenesmodulates innate immunity by inducing tumor necrosis factor α
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منابع مشابه
Tumor necrosis factor superfamily in innate immunity and inflammation.
The tumor necrosis factor superfamily (TNFSF) and its corresponding receptor superfamily (TNFRSF) form communication pathways required for developmental, homeostatic, and stimulus-responsive processes in vivo. Although this receptor-ligand system operates between many different cell types and organ systems, many of these proteins play specific roles in immune system function. The TNFSF and TNFR...
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Tumor necrosis factor (TNF)-alpha and lymphotoxin (LT) alpha/beta play multiple roles in the development and function of the immune system. This article focuses on three important aspects of the effects of these cytokines on the immune response and on autoimmunity. In several experimental systems (Jurkat T cells, murine T-cell hybridomas), TNF-alpha appears to cause a downregulation of signalin...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2010
ISSN: 0928-8244,1574-695X
DOI: 10.1111/j.1574-695x.2010.00666.x